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mestinon should be discontinued at the first sign of nerve agent poisoning since it may exacerbate the effects of a sub-lethal exposure to soman.
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the groups given mestinon-sr as well as atropine and 2-pam showed increases in the soman ld 50 of at least 40 fold compared to the untreated control group and at least 25 fold compared to the atropine 2-pam group.
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Mestinon is a cholinesterase inhibitor, and its active ingredient is pyridostigmine.
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