In drug combination studies of tenofovir with nrtis abacavir, didanosine, lamivudine, stavudine, zalcitabine, and zidovudine , nnrtis delavirdine, efavirenz, and nevirapine , and pis amprenavir, indinavir, nelfinavir, ritonavir, and saquinavir , additive to synergistic effects were observed.
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when coadministered with indinavir, a dose reduction of rifabutin to 50 the standard dosage and an increase of indinavir to 1,000 mg every 8 h is recommended.
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simultaneous determination of the hiv drugs indinavir, amprenavir, saquinavir, ritonavir, lopinavir, nelfinavir, the nelfinavir hydroxymetabolite m8, and nevirapine in human plasma by reversed-phase high-performance liquid chromatography.
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gender the effect of gender on the pharmacokinetics of indinavir was evaluated in 10 hiv seropositive women who received crixivan 800 mg every 8 hours with zidovudine 200 mg every 8 hours and lamivudine 150 mg twice a day for one week.
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